| A Summary of Pantoprazole side effects appearing on different organs/body systems | |
| CNS | Headache, dizziness, asthenia, vertigo, insomnia, apathy, anxiety, prickling sensation, dream abnormalities |
| GIT | Diarrhea, abdominal pain, nausea, vomiting, constipation, dry mouth, tongue atrophy, C. difficile diarrhea |
| Respiratory system | Upper respiratory infection symptoms, cough, epistaxis, pneumonia |
| Others | Back pain, fever, vitamin B12 deficiency, loss of bone density, bone fractures, decreased magnesium levels, thrombophlebitis with IV use |
It acts by preventing the conversion of angiotensin I to angiotensin II (a potent vasoconstrictor), and thus, decreases blood pressure.
Lisinopril can cause various adverse reactions, most commonly rash and persistent dry cough. To minimize these effects a reduction of dosage may necessary.
Pantoprazole (Protonix) is a proton pump inhibitor that acts by reducing the amount of acid the stomach produces, hence it is used for diseases that are caused/worsened by the excess of stomach acid such as peptic ulcer, duodenal ulcers and GERD.
Usually, Pantoprazole will not cause any side effects; however, if you experience any symptom, they will often be mild and will diminish once you stop taking the drug.
- Asthenia
- Sleep disorders
- Gastrointestinal disorder
- Hyperlipidemia
- Angioedema
- Changes in weight
- Toxic epidermal necrolysis
- Stevens-Johnson syndrome
- Thrombocytopenia
- Hip fracture
- Rhabdomyolysis
- Acute interstitial nephritis
- Muscle spasm
- Electrolyte imbalance
Pantoprazole overdose symptoms may include hyperglycemia and C.difficile associated diarrhea.
1. Kizior, R.J. and Hodgson, B.B. (2018). Saunders nursing drug handbook 2019. Philadelphia: Saunders.
2. Joint formulary committee, BNF 80 (The British National Formulary), 80th Revised edition, Pharmaceutical Press, London, United Kingdom, [2020]
3. Williams and Wolters Kluwer Health (2012). Nursing 2012 drug handbook. Philadelphia, Pa.: Wolters Kluwer Health/Lippincott Williams & Wilkins.
Pantoprazole (Protonix) belongs to a group of medicine known as PPIs. It’s commonly used to treat stomach and intestinal ulcers, acid reflux, heartburn, and Zollinger Ellison syndrome. Click to read more information about Pantoprazole.
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